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Role of gut microbiota-derived signals in the regulation of gastrointestinal motility.
Zheng Z, Tang J, Hu Y, Zhang W. Zheng Z, et al. Front Med (Lausanne). 2022 Jul 22;9:961703. doi: 10.3389/fmed.2022.961703. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35935766 Free PMC article. Review.
The gastrointestinal (GI) tract harbors trillions of commensal microbes, called the gut microbiota, which plays a significant role in the regulation of GI physiology, particularly GI motility. ...In this perspective, we overview the current knowledge o …
The gastrointestinal (GI) tract harbors trillions of commensal microbes, called the gut microbiota, which plays a significant role
Role of bile in regulation of gut motility.
Hellström PM, Nilsson I, Svenberg T. Hellström PM, et al. J Intern Med. 1995 Apr;237(4):395-402. doi: 10.1111/j.1365-2796.1995.tb01193.x. J Intern Med. 1995. PMID: 7714463 Review.
In conclusion, data indicate that motilin is released to the circulation by the biliary output and induces phase 3 of MMC. The induced phase 3 propels bile acids along the gut to promote their absorption in the distal intestine. ...In such a manner the MMC may be wi …
In conclusion, data indicate that motilin is released to the circulation by the biliary output and induces phase 3 of MMC. The induced phase …
Bile Acid-Related Regulation of Mucosal Inflammation and Intestinal Motility: From Pathogenesis to Therapeutic Application in IBD and Microscopic Colitis.
Di Vincenzo F, Puca P, Lopetuso LR, Petito V, Masi L, Bartocci B, Murgiano M, De Felice M, Petronio L, Gasbarrini A, Scaldaferri F. Di Vincenzo F, et al. Nutrients. 2022 Jun 27;14(13):2664. doi: 10.3390/nu14132664. Nutrients. 2022. PMID: 35807844 Free PMC article. Review.
We decided to deeply analyze the role of bile acids in these complex interactions and their metabolism in the modulation of gut microbiota, and thus intestinal mucosa inflammation. ...Finally, we discuss the role of bile acid in current and poss …
We decided to deeply analyze the role of bile acids in these complex interactions and their metabolism in the modulation of …
Bile Acid and Gut Microbiota in Irritable Bowel Syndrome.
Min YW, Rezaie A, Pimentel M. Min YW, et al. J Neurogastroenterol Motil. 2022 Oct 30;28(4):549-561. doi: 10.5056/jnm22129. J Neurogastroenterol Motil. 2022. PMID: 36250362 Free PMC article. Review.
Gut microbiota and their metabolites like bile acid (BA) have been investigated as causes of irritable bowel syndrome (IBS) symptoms. ...BAs have prosecretory effects and regulates gut motility. BAs can also affect gut sensitivity. Becaus
Gut microbiota and their metabolites like bile acid (BA) have been investigated as causes of irritable bowel syndrome (IBS) sy
Effects of a ketogenic and low-fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer's disease.
Dilmore AH, Martino C, Neth BJ, West KA, Zemlin J, Rahman G, Panitchpakdi M, Meehan MJ, Weldon KC, Blach C, Schimmel L, Kaddurah-Daouk R, Dorrestein PC, Knight R, Craft S; Alzheimer's Gut Microbiome Project Consortium. Dilmore AH, et al. Alzheimers Dement. 2023 Nov;19(11):4805-4816. doi: 10.1002/alz.13007. Epub 2023 Apr 5. Alzheimers Dement. 2023. PMID: 37017243
INTRODUCTION: The ketogenic diet (KD) is an intriguing therapeutic candidate for Alzheimer's disease (AD) given its protective effects against metabolic dysregulation and seizures. Gut microbiota are essential for KD-mediated neuroprotection against seizures as well as mod …
INTRODUCTION: The ketogenic diet (KD) is an intriguing therapeutic candidate for Alzheimer's disease (AD) given its protective effects again …
Coordinate regulation of gallbladder motor function in the gut-liver axis.
Portincasa P, Di Ciaula A, Wang HH, Palasciano G, van Erpecum KJ, Moschetta A, Wang DQ. Portincasa P, et al. Hepatology. 2008 Jun;47(6):2112-26. doi: 10.1002/hep.22204. Hepatology. 2008. PMID: 18506897 Review.
Indeed, a fine coordinated hepatobiliary and gastrointestinal function, including gallbladder motility in the fasting and postprandial state, is of crucial importance to prevent crystallization and precipitation of excess cholesterol in gallbladder bile. Also, gallb …
Indeed, a fine coordinated hepatobiliary and gastrointestinal function, including gallbladder motility in the fasting and postprandia …
Role of cholecystokinin in the regulation of gastrointestinal motility.
Grider JR. Grider JR. J Nutr. 1994 Aug;124(8 Suppl):1334S-1339S. doi: 10.1093/jn/124.suppl_8.1334S. J Nutr. 1994. PMID: 8064380 Review.
Cholecystokinin, a hormone released from endocrine cells of the upper small intestine in response to amino acids and fatty acids in chyme, has potent effects on gut smooth muscle contractility. Depending on the region of the gut, the effect of cholecystokinin may be …
Cholecystokinin, a hormone released from endocrine cells of the upper small intestine in response to amino acids and fatty acids in chyme, h …
Gut Microbiota-Dependent Modulation of Energy Metabolism.
Heiss CN, Olofsson LE. Heiss CN, et al. J Innate Immun. 2018;10(3):163-171. doi: 10.1159/000481519. Epub 2017 Nov 8. J Innate Immun. 2018. PMID: 29131106 Free PMC article. Review.
Taken together, these findings indicate a role for the gut microbiota in obesity and suggest that the gut microbiota could be targeted to improve metabolic diseases like obesity. This review focuses on the role of the gut microbiota in energy ba …
Taken together, these findings indicate a role for the gut microbiota in obesity and suggest that the gut microbiota co …
The immunomodulatory role of bile acids.
Sipka S, Bruckner G. Sipka S, et al. Int Arch Allergy Immunol. 2014;165(1):1-8. doi: 10.1159/000366100. Epub 2014 Sep 24. Int Arch Allergy Immunol. 2014. PMID: 25277277 Review.
This review focuses on the present knowledge regarding the physiologic and pathologic role of bile acids and their immunomodulatory role, with particular attention to bacterial lipopolysaccharides (endotoxins) and bile acid and immunological disorders. …
This review focuses on the present knowledge regarding the physiologic and pathologic role of bile acids and their immunomodul …
Bile is a promising gut nutrient that inhibits intestinal bacterial translocation and promotes gut motility via an interleukin-6-related pathway in an animal model of endotoxemia.
Sun X, Zhu S, Tonnessen TI, Yang R. Sun X, et al. Nutrition. 2021 Apr;84:111064. doi: 10.1016/j.nut.2020.111064. Epub 2020 Nov 16. Nutrition. 2021. PMID: 33418232 Free article.
Bile acids are nutrient-signaling hormones that have a significant impact on gut barrier function and motility, and the gut is considered the origin of systemic inflammation. Therefore, healthy exogenous bile could be a promising gut nutr
Bile acids are nutrient-signaling hormones that have a significant impact on gut barrier function and motility, and the
27 results