New hypothesis of developmental anomalies of the anterior chamber associated with glaucoma.

Kupfer C; Kaiser-Kupfer MI

New hypothesis of developmental anomalies of the anterior chamber associated with glaucoma.

Transactions of the Ophthalmological Societies of the United Kingdom, 01 Jan 1978, 98(2):213-215
PMID: 286450

Abstract

The group of congenital and developmental anomalies of the anterior chamber associated with increased intraocular pressure has been difficult to interpret from an embryologic perspective which would take into account the ocular defects as well as associated systemic abnormalities. A new hypothesis is presented which suggests that the ocular and systemic defects can be explained by abnormalities in migration or terminal induction of neural-crest cells. These cells represent the initial population which differentiates into the diversity of cell types that appear to be involved in both the ocular and systemic manifestation of this group of anterior chamber anomalies.

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Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted under certain circumstances. There are six different Creative Commons licenses available, see the copyright license for this article to understand what type of reuse is permitted.
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Noggin producing, MyoD-positive cells are crucial for eye development.
Gerhart J, Pfautz J, Neely C, Elder J, DuPrey K, Menko AS, Knudsen K, George-Weinstein M
Dev Biol, 336(1):30-41, 22 Sep 2009
Cited by: 18 articles | PMID: 19778533 | PMCID: PMC2783511
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The mouse anterior chamber angle and trabecular meshwork develop without cell death.
Smith RS, Zabaleta A, Savinova OV, John SW
BMC Dev Biol, 1:3, 14 Feb 2001
Cited by: 80 articles | PMID: 11228591 | PMCID: PMC31337
Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted under certain circumstances. There are six different Creative Commons licenses available, see the copyright license for this article to understand what type of reuse is permitted.
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New hypothesis of developmental anomalies of the anterior chamber associated with glaucoma.

Abstract

Citations & impact

Impact metrics

Citations of article over time

Article citations

Geographical Variability in CYP1B1 Mutations in Primary Congenital Glaucoma.

Generation of a new mouse model of glaucoma characterized by reduced expression of the AP-2β and AP-2δ proteins.

Conditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma.

Noggin producing, MyoD-positive cells are crucial for eye development.

The mouse anterior chamber angle and trabecular meshwork develop without cell death.

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