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Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans.
Kempen HJ, Glatz JF, Gevers Leuven JA, van der Voort HA, Katan MB. Kempen HJ, et al. J Lipid Res. 1988 Sep;29(9):1149-55. J Lipid Res. 1988. PMID: 3183524 Free article.
The power of serum lathosterol concentration as an indicator of whole-body cholesterol synthesis was investigated in 47 human volunteers consuming two diets differing in fatty acid composition. ...The ratio was lowere …
The power of serum lathosterol concentration as an indicator of whole-body cholesterol s …
Stearate-enriched plant sterol esters lower serum LDL cholesterol concentration in normo- and hypercholesterolemic adults.
Carr TP, Krogstrand KL, Schlegel VL, Fernandez ML. Carr TP, et al. J Nutr. 2009 Aug;139(8):1445-50. doi: 10.3945/jn.109.106328. Epub 2009 Jun 17. J Nutr. 2009. PMID: 19535421 Free article. Clinical Trial.
Participants consumed 3 g/d (1 g three times per day with meals) of either PS esters or placebo delivered in capsules. Serum LDL cholesterol concentration significantly decreased 0.42 mmol/L (11%) and the LDL:HDL cholesterol ratio decreased 10% with PS …
Participants consumed 3 g/d (1 g three times per day with meals) of either PS esters or placebo delivered in capsules. Serum LDL c …
Comparative effects of simvastatin and pravastatin on cholesterol synthesis in patients with primary hypercholesterolemia.
Feillet C, Farnier M, Monnier LH, Percheron C, Colette C, Descomps B, Crastes De Paulet A. Feillet C, et al. Atherosclerosis. 1995 Dec;118(2):251-8. doi: 10.1016/0021-9150(95)05611-4. Atherosclerosis. 1995. PMID: 8770319 Clinical Trial.
Serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) lathosterol (latho) concentrations and lathosterol/cholesterol (latho/chol) ratios (the latter two are considered as reliable indices of whole …
Serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) lathosterol (latho) concentrations …
Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women.
Plat J, Mensink RP. Plat J, et al. FASEB J. 2002 Feb;16(2):258-60. doi: 10.1096/fj.01-0653fje. Epub 2001 Dec 28. FASEB J. 2002. PMID: 11772951 Clinical Trial.
Based on these results, we suggest that the higher LDL receptor expression contributed to a lowered LDL formation along the apoB cascade. Whole body cholesterol synthesis increased, as indicated by the rise in serum cholesterol-sta …
Based on these results, we suggest that the higher LDL receptor expression contributed to a lowered LDL formation along the apoB cascade. …