Candida albicans interactions with epithelial cells and mucosal immunity

Microbes Infect. 2011 Nov;13(12-13):963-76. doi: 10.1016/j.micinf.2011.06.009. Epub 2011 Jul 14.

Abstract

Candida albicans interactions with epithelial cells are critical for commensal growth, fungal pathogenicity and host defence. This review will outline our current understanding of C. albicans-epithelial interactions and will discuss how this may lead to the induction of a protective mucosal immune response.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Candida albicans / growth & development
  • Candida albicans / pathogenicity
  • Candida albicans / physiology*
  • Candidiasis / immunology*
  • Candidiasis / microbiology
  • Endocytosis
  • Epithelial Cells / immunology
  • Epithelial Cells / microbiology*
  • Host-Pathogen Interactions
  • Humans
  • Immunity, Mucosal / immunology