Bacteriophages suppress CRISPR-Cas immunity using RNA-based anti-CRISPRs.
Camara-Wilpert S, Mayo-Muñoz D, Russel J, Fagerlund RD, Madsen JS, Fineran PC, Sørensen SJ, Pinilla-Redondo R.
Camara-Wilpert S, et al.
Nature. 2023 Nov;623(7987):601-607. doi: 10.1038/s41586-023-06612-5. Epub 2023 Oct 18.
Nature. 2023.
PMID: 37853129
Free PMC article.
We identified Racr candidates for almost all CRISPR-Cas types encoded by a diverse range of viruses and plasmids, often in the genetic context of other anti-CRISPR genes(5). Functional testing of nine candidates spanning the two CRISPR-Cas classes confirmed their st …
We identified Racr candidates for almost all CRISPR-Cas types encoded by a diverse range of viruses and plasmids, often in the genetic conte …