Abstract. The extraction, isolation and characterization of 29 natural products contained in Ginkgo biloba have been described, which we have now tested for ...
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The results indicate that G. biloba extract pretreatment significantly induced the expression of CYP3A protein and mRNA and increased CYP3A activity, and there ...
Abstract. The Ginkgo biloba extract EGb761 was tested for its ability to inhibit the major human cytochrome P450 enzymes (CYPs). The full extract was found to ...
Jul 27, 2022 · Cytochrome P450 (CYP450), a heme-binding protein, is composed of heme protein, flavin protein, and phospholipids, which is mainly distributed in ...
Our results indicate that Ginkgo biloba L. (GB) and Selaginella tamariscina (P. Beauv.) Spring (ST) display the strongest inhibitory effects toward CYP3A4, and ...
Abstract. The extraction, isolation and characterization of 29 natural products contained in Ginkgo biloba have been described, which we have now tested fo.
The constituents of Ginkgo biloba extract have been demonstrated to induce gene expression of the. CYP450 enzymes. We report a case in which a potential drug ...
Sep 1, 2022 · The cytochrome P450s belong to CYP families that diversifies in pre-seed plants and gymnosperms, but are not preserved in angiosperms. Our work ...
Ginkgo biloba is one of the most popular herbal ... 2. The activity of CYP450 was measured by the quantification of six metabolites from multiple cytochrome ...
Dec 21, 2011 · In vitro studies with human enzymes showed that Ginkgo biloba may inhibit CYPs [18–21]. Such inhibition has been associated with ginkgolic acids ...