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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 1
1971 1
1974 1
1975 1
1976 1
1977 2
1982 1
1983 1
1985 2
1986 1
1988 2
1989 1
1990 1
1991 1
1992 3
1993 1
1994 2
1995 1
1997 3
1998 1
1999 5
2000 11
2001 19
2002 22
2003 22
2004 18
2005 23
2006 26
2007 28
2008 21
2009 25
2010 36
2011 45
2012 45
2013 47
2014 45
2015 44
2016 64
2017 90
2018 96
2019 102
2020 124
2021 107
2022 75
2023 81
2024 25

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1,090 results

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Page 1
Mitochondria and Critical Illness.
Supinski GS, Schroder EA, Callahan LA. Supinski GS, et al. Chest. 2020 Feb;157(2):310-322. doi: 10.1016/j.chest.2019.08.2182. Epub 2019 Sep 5. Chest. 2020. PMID: 31494084 Free PMC article. Review.
Classically, mitochondria have largely been believed to influence the development of illness by modulating cell metabolism and determining the rate of production of high-energy phosphate compounds (eg, adenosine triphosphate). It is now recognized that this view is simplis …
Classically, mitochondria have largely been believed to influence the development of illness by modulating cell metabolism and determ …
Impact of Melatonin on Skeletal Muscle and Exercise.
Stacchiotti A, Favero G, Rodella LF. Stacchiotti A, et al. Cells. 2020 Jan 24;9(2):288. doi: 10.3390/cells9020288. Cells. 2020. PMID: 31991655 Free PMC article. Review.
Mitochondria are the favorite target of melatonin, which maintains them efficiently, scavenging free radicals and reducing oxidative damage. ...Furthermore, we analyze the emerging impact of melatonin on physical activity. Finally, we consider the newest evid …
Mitochondria are the favorite target of melatonin, which maintains them efficiently, scavenging free radicals and reducing oxi …
Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs.
Park S, Ham J, Yang C, Park W, Park H, An G, Song J, Hong T, Park SJ, Kim HS, Song G, Lim W. Park S, et al. J Pineal Res. 2023 Jan;74(1):e12842. doi: 10.1111/jpi.12842. Epub 2022 Nov 27. J Pineal Res. 2023. PMID: 36401340
This was achieved through messenger RNA-mediated downregulation of respiratory complex subunits. Melatonin inhibited the PI3K/AKT and ERK1/2 pathways and the mitochondria-associated membrane axis and further suppressed the migration of endometriotic epithelial and s …
This was achieved through messenger RNA-mediated downregulation of respiratory complex subunits. Melatonin inhibited the PI3K/AKT and …
Feeding mitochondria: Potential role of nutritional components to improve critical illness convalescence.
Wesselink E, Koekkoek WAC, Grefte S, Witkamp RF, van Zanten ARH. Wesselink E, et al. Clin Nutr. 2019 Jun;38(3):982-995. doi: 10.1016/j.clnu.2018.08.032. Epub 2018 Aug 31. Clin Nutr. 2019. PMID: 30201141 Free article. Review.
We have addressed the role of B vitamins, ascorbic acid, alpha-tocopherol, selenium, zinc, coenzyme Q10, caffeine, melatonin, carnitine, nitrate, lipoic acid and taurine in mitochondrial function. B vitamins and lipoic acid are essential in the tricarboxylic acid cycle, wh …
We have addressed the role of B vitamins, ascorbic acid, alpha-tocopherol, selenium, zinc, coenzyme Q10, caffeine, melatonin, carniti …
Melatonin, mitochondria and hypertension.
Baltatu OC, Amaral FG, Campos LA, Cipolla-Neto J. Baltatu OC, et al. Cell Mol Life Sci. 2017 Nov;74(21):3955-3964. doi: 10.1007/s00018-017-2613-y. Epub 2017 Aug 8. Cell Mol Life Sci. 2017. PMID: 28791422 Review.
Melatonin, due to its multiple means and mechanisms of action, plays a fundamental role in the regulation of the organismal physiology by fine tunning several functions. ...Besides, the systemic management of several processes, melatonin acts on mitochondria …
Melatonin, due to its multiple means and mechanisms of action, plays a fundamental role in the regulation of the organismal physiolog …
Melatonin, mitochondria, and the skin.
Slominski AT, Zmijewski MA, Semak I, Kim TK, Janjetovic Z, Slominski RM, Zmijewski JW. Slominski AT, et al. Cell Mol Life Sci. 2017 Nov;74(21):3913-3925. doi: 10.1007/s00018-017-2617-7. Epub 2017 Aug 12. Cell Mol Life Sci. 2017. PMID: 28803347 Free PMC article. Review.
Moreover, they attenuate the pathological processes including carcinogenesis and other hyperproliferative/inflammatory conditions. Interestingly, mitochondria appear to be a central hub of melatonin metabolism in the skin cells. ...Of note, some metabolites exhibit …
Moreover, they attenuate the pathological processes including carcinogenesis and other hyperproliferative/inflammatory conditions. Interesti …
Melatonin reshapes the mitochondrial network and promotes intercellular mitochondrial transfer via tunneling nanotubes after ischemic-like injury in hippocampal HT22 cells.
Nasoni MG, Carloni S, Canonico B, Burattini S, Cesarini E, Papa S, Pagliarini M, Ambrogini P, Balduini W, Luchetti F. Nasoni MG, et al. J Pineal Res. 2021 Aug;71(1):e12747. doi: 10.1111/jpi.12747. Epub 2021 Jun 14. J Pineal Res. 2021. PMID: 34085316 Free PMC article.
Maintaining mitochondrial dynamics is crucial to cell function and survival. The present study aimed to assess the effects of melatonin on mitochondrial dynamics, TNT formation, and mitochondria transfer in HT22 cells exposed to oxygen/glucose deprivation followed b …
Maintaining mitochondrial dynamics is crucial to cell function and survival. The present study aimed to assess the effects of melatonin …
Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction.
Xu S, Li L, Wu J, An S, Fang H, Han Y, Huang Q, Chen Z, Zeng Z. Xu S, et al. Front Immunol. 2021 Mar 12;12:625627. doi: 10.3389/fimmu.2021.625627. eCollection 2021. Front Immunol. 2021. PMID: 33790896 Free PMC article.
However, whether melatonin attenuates small-intestine injury along with the precise underlying mechanism remain to be elucidated. ...Correspondingly, melatonin treatment triggered SOD2 deacetylation and increased SOD2 activity and subsequently reduced oxidative stre …
However, whether melatonin attenuates small-intestine injury along with the precise underlying mechanism remain to be elucidated. ... …
Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential.
Huo X, Wang C, Yu Z, Peng Y, Wang S, Feng S, Zhang S, Tian X, Sun C, Liu K, Deng S, Ma X. Huo X, et al. J Pineal Res. 2017 May;62(4). doi: 10.1111/jpi.12390. J Pineal Res. 2017. PMID: 28099762
For the first time, PEPT1/2 were identified to localize in the mitochondrial membrane of human cancer cell lines of PC3 and U118. PEPT1/2 facilitated the transportation of melatonin into mitochondria. Melatonin accumulation in mitochondria induced apop …
For the first time, PEPT1/2 were identified to localize in the mitochondrial membrane of human cancer cell lines of PC3 and U118. PEPT1/2 fa …
Melatonin, mitochondria, and the cancer cell.
Proietti S, Cucina A, Minini M, Bizzarri M. Proietti S, et al. Cell Mol Life Sci. 2017 Nov;74(21):4015-4025. doi: 10.1007/s00018-017-2612-z. Epub 2017 Aug 7. Cell Mol Life Sci. 2017. PMID: 28785807 Review.
The long-recognized fact that oxidative stress within mitochondria is a hallmark of mitochondrial dysfunction has stimulated the development of mitochondria-targeted antioxidant therapies. Melatonin should be included among the pharmacological agents able to …
The long-recognized fact that oxidative stress within mitochondria is a hallmark of mitochondrial dysfunction has stimulated the deve …
1,090 results