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Gut microbiota in health and disease.
Sekirov I, Russell SL, Antunes LC, Finlay BB. Sekirov I, et al. Physiol Rev. 2010 Jul;90(3):859-904. doi: 10.1152/physrev.00045.2009. Physiol Rev. 2010. PMID: 20664075 Free article. Review.
Gut microbiota is an assortment of microorganisms inhabiting the length and width of the mammalian gastrointestinal tract. ...The advances in modeling and analysis of gut microbiota will further our knowledge of their role in health and disease, allowi …
Gut microbiota is an assortment of microorganisms inhabiting the length and width of the mammalian gastrointestinal tract. ... …
Host-bacterial mutualism in the human intestine.
Bäckhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Bäckhed F, et al. Science. 2005 Mar 25;307(5717):1915-20. doi: 10.1126/science.1104816. Science. 2005. PMID: 15790844 Review.
New studies are revealing how the gut microbiota has coevolved with us and how it manipulates and complements our biology in ways that are mutually beneficial. We are also starting to understand how certain keystone members of the microbiota operate to mainta …
New studies are revealing how the gut microbiota has coevolved with us and how it manipulates and complements our biology in w …
A human gut microbial gene catalogue established by metagenomic sequencing.
Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, Nielsen T, Pons N, Levenez F, Yamada T, Mende DR, Li J, Xu J, Li S, Li D, Cao J, Wang B, Liang H, Zheng H, Xie Y, Tap J, Lepage P, Bertalan M, Batto JM, Hansen T, Le Paslier D, Linneberg A, Nielsen HB, Pelletier E, Renault P, Sicheritz-Ponten T, Turner K, Zhu H, Yu C, Li S, Jian M, Zhou Y, Li Y, Zhang X, Li S, Qin N, Yang H, Wang J, Brunak S, Doré J, Guarner F, Kristiansen K, Pedersen O, Parkhill J, Weissenbach J; MetaHIT Consortium; Bork P, Ehrlich SD, Wang J. Qin J, et al. Nature. 2010 Mar 4;464(7285):59-65. doi: 10.1038/nature08821. Nature. 2010. PMID: 20203603 Free PMC article.
To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. ...Over 99% of the genes are bacterial, indicating that the entire cohort harbours between 1,000 and 1,150 prevalent bacterial species and each individu …
To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. ...Over 99% …
Principles and clinical implications of the brain-gut-enteric microbiota axis.
Rhee SH, Pothoulakis C, Mayer EA. Rhee SH, et al. Nat Rev Gastroenterol Hepatol. 2009 May;6(5):306-14. doi: 10.1038/nrgastro.2009.35. Nat Rev Gastroenterol Hepatol. 2009. PMID: 19404271 Free PMC article. Review.
While bidirectional brain-gut interactions are well known mechanisms for the regulation of gut function in both healthy and diseased states, a role of the enteric flora--including both commensal and pathogenic organisms--in these interactions has only been recognize …
While bidirectional brain-gut interactions are well known mechanisms for the regulation of gut function in both healthy and di …
A core gut microbiome in obese and lean twins.
Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE, Sogin ML, Jones WJ, Roe BA, Affourtit JP, Egholm M, Henrissat B, Heath AC, Knight R, Gordon JI. Turnbaugh PJ, et al. Nature. 2009 Jan 22;457(7228):480-4. doi: 10.1038/nature07540. Epub 2008 Nov 30. Nature. 2009. PMID: 19043404 Free PMC article.
The human distal gut harbours a vast ensemble of microbes (the microbiota) that provide important metabolic capabilities, including the ability to extract energy from otherwise indigestible dietary polysaccharides. Studies of a few unrelated, healthy adults have rev …
The human distal gut harbours a vast ensemble of microbes (the microbiota) that provide important metabolic capabilities, incl …
Prebiotic effects: metabolic and health benefits.
Roberfroid M, Gibson GR, Hoyles L, McCartney AL, Rastall R, Rowland I, Wolvers D, Watzl B, Szajewska H, Stahl B, Guarner F, Respondek F, Whelan K, Coxam V, Davicco MJ, Léotoing L, Wittrant Y, Delzenne NM, Cani PD, Neyrinck AM, Meheust A. Roberfroid M, et al. Br J Nutr. 2010 Aug;104 Suppl 2:S1-63. doi: 10.1017/S0007114510003363. Br J Nutr. 2010. PMID: 20920376 Review.
Promising beneficial effects have been demonstrated in some preliminary studies, including changes in gut microbiota composition (especially increase in bifidobacteria concentration). ...Some of these studies (including one human trial) have also reported that, in s …
Promising beneficial effects have been demonstrated in some preliminary studies, including changes in gut microbiota compositi …
Bacterial community variation in human body habitats across space and time.
Costello EK, Lauber CL, Hamady M, Fierer N, Gordon JI, Knight R. Costello EK, et al. Science. 2009 Dec 18;326(5960):1694-7. doi: 10.1126/science.1177486. Epub 2009 Nov 5. Science. 2009. PMID: 19892944 Free PMC article.
To obtain an integrated view of the spatial and temporal distribution of the human microbiota, we surveyed bacteria from up to 27 sites in seven to nine healthy adults on four occasions. ...Several skin locations harbored more diverse communities than the gut and mo …
To obtain an integrated view of the spatial and temporal distribution of the human microbiota, we surveyed bacteria from up to 27 sit …
The gut microbiota shapes intestinal immune responses during health and disease.
Round JL, Mazmanian SK. Round JL, et al. Nat Rev Immunol. 2009 May;9(5):313-23. doi: 10.1038/nri2515. Nat Rev Immunol. 2009. PMID: 19343057 Free PMC article. Review.
In this Review we discuss findings indicating that developmental aspects of the adaptive immune system are influenced by bacterial colonization of the gut. We also highlight the molecular pathways that mediate host-symbiont interactions that regulate proper immune function …
In this Review we discuss findings indicating that developmental aspects of the adaptive immune system are influenced by bacterial colonizat …
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.
Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D, Schilter HC, Rolph MS, Mackay F, Artis D, Xavier RJ, Teixeira MM, Mackay CR. Maslowski KM, et al. Nature. 2009 Oct 29;461(7268):1282-6. doi: 10.1038/nature08530. Nature. 2009. PMID: 19865172 Free PMC article.
However, recent evidence indicates that normal intestinal microbiota might also positively influence immune responses, and protect against the development of inflammatory diseases. One of these elements may be short-chain fatty acids (SCFAs), which are produced by fermenta …
However, recent evidence indicates that normal intestinal microbiota might also positively influence immune responses, and protect ag …
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa.
De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, Collini S, Pieraccini G, Lionetti P. De Filippo C, et al. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14691-6. doi: 10.1073/pnas.1005963107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679230 Free PMC article.
Gut microbial composition depends on different dietary habits just as health depends on microbial metabolism, but the association of microbiota with different diets in human populations has not yet been shown. ...Also, Enterobacteriaceae (Shigella and Escherichia) w …
Gut microbial composition depends on different dietary habits just as health depends on microbial metabolism, but the association of …
843 results