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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1969 1
1970 1
1972 1
1974 2
1975 1
1976 2
1977 1
1979 2
1981 2
1982 3
1983 2
1984 8
1985 6
1986 5
1987 4
1988 10
1989 10
1990 12
1991 14
1992 12
1993 12
1994 17
1995 27
1996 26
1997 27
1998 25
1999 33
2000 47
2001 42
2002 34
2003 43
2004 30
2005 36
2006 29
2007 40
2008 38
2009 34
2010 39
2011 53
2012 44
2013 48
2014 47
2015 41
2016 50
2017 47
2018 43
2019 47
2020 35
2021 27
2022 24
2023 34
2024 7

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1,121 results

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Page 1
Human iPSC-derived midbrain organoids functionally integrate into striatum circuits and restore motor function in a mouse model of Parkinson's disease.
Zheng X, Han D, Liu W, Wang X, Pan N, Wang Y, Chen Z. Zheng X, et al. Theranostics. 2023 Apr 29;13(8):2673-2692. doi: 10.7150/thno.80271. eCollection 2023. Theranostics. 2023. PMID: 37215566 Free PMC article.
Rationale: Parkinson's disease (PD) is a prevalent neurodegenerative disorder that is characterized by degeneration of dopaminergic neurons (DA) at the substantia nigra pas compacta (SNpc). ...
Rationale: Parkinson's disease (PD) is a prevalent neurodegenerative disorder that is characterized by degeneration of …
Histamine and the striatum.
Bolam JP, Ellender TJ. Bolam JP, et al. Neuropharmacology. 2016 Jul;106:74-84. doi: 10.1016/j.neuropharm.2015.08.013. Epub 2015 Aug 11. Neuropharmacology. 2016. PMID: 26275849 Free PMC article. Review.
Furthermore, we will discuss recent findings of histaminergic dysfunction in several basal ganglia disorders, including in Parkinson's disease and most prominently, in Tourette's syndrome, which has led to a resurgence of interest in this neuromodulato …
Furthermore, we will discuss recent findings of histaminergic dysfunction in several basal ganglia disorders, including in Parkins …
Cellular and Synaptic Dysfunctions in Parkinson's Disease: Stepping out of the Striatum.
Mallet N, Delgado L, Chazalon M, Miguelez C, Baufreton J. Mallet N, et al. Cells. 2019 Aug 29;8(9):1005. doi: 10.3390/cells8091005. Cells. 2019. PMID: 31470672 Free PMC article. Review.
This degeneration causes cellular and synaptic dysfunctions in the BG network, which are responsible for the appearance of the motor symptoms of Parkinson's disease. Dopamine (DA) modulation and the consequences of its loss on the striatal microcircuit have b …
This degeneration causes cellular and synaptic dysfunctions in the BG network, which are responsible for the appearance of the motor symptom …
Subregional analysis of striatum iron in Parkinson's disease and rapid eye movement sleep behaviour disorder.
Alushaj E, Hemachandra D, Kuurstra A, Menon RS, Ganjavi H, Sharma M, Kashgari A, Barr J, Reisman W, Khan AR, MacDonald PA. Alushaj E, et al. Neuroimage Clin. 2023;40:103519. doi: 10.1016/j.nicl.2023.103519. Epub 2023 Sep 28. Neuroimage Clin. 2023. PMID: 37797434 Free PMC article.
The loss of dopamine in the striatum underlies motor symptoms of Parkinson's disease (PD). Rapid eye movement sleep behaviour disorder (RBD) is considered prodromal PD and has shown similar neural changes in the striatum. ...
The loss of dopamine in the striatum underlies motor symptoms of Parkinson's disease (PD). Rapid eye movement sleep beh …
Mapping microstructural gradients of the human striatum in normal aging and Parkinson's disease.
Drori E, Berman S, Mezer AA. Drori E, et al. Sci Adv. 2022 Jul 15;8(28):eabm1971. doi: 10.1126/sciadv.abm1971. Epub 2022 Jul 15. Sci Adv. 2022. PMID: 35857492 Free PMC article.
., gradients) in the striatum is essential for understanding the function of the basal ganglia in both health and disease. We developed a method to identify and quantify gradients of microstructure in the single human brain in vivo. ...Furthermore, we found cortico-striata …
., gradients) in the striatum is essential for understanding the function of the basal ganglia in both health and disease. We develop …
Reward processing dysfunction in ventral striatum and orbitofrontal cortex in Parkinson's disease.
du Plessis S, Bossert M, Vink M, van den Heuvel L, Bardien S, Emsley R, Buckle C, Seedat S, Carr J. du Plessis S, et al. Parkinsonism Relat Disord. 2018 Mar;48:82-88. doi: 10.1016/j.parkreldis.2017.12.024. Epub 2017 Dec 24. Parkinsonism Relat Disord. 2018. PMID: 29307561
BACKGROUND: Parkinson's disease is a growing concern as the longevity of the world's population steadily increases. ...There has been little investigation of reward processing in terms of anticipation and reward outcome in Parkinson's disease …
BACKGROUND: Parkinson's disease is a growing concern as the longevity of the world's population steadily increases. ... …
"Depressed" caudate and ventral striatum dopamine transporter availability in de novo Depressed Parkinson's disease.
Yoo SW, Oh YS, Hwang EJ, Ryu DW, Lee KS, Lyoo CH, Kim JS. Yoo SW, et al. Neurobiol Dis. 2019 Dec;132:104563. doi: 10.1016/j.nbd.2019.104563. Epub 2019 Aug 1. Neurobiol Dis. 2019. PMID: 31377233 Free article.
Depression can occur before the onset of motor symptoms in Parkinson's disease (PD) patients. The pathophysiology of depression in PD involves various brain regions and relevant functional circuits. ...
Depression can occur before the onset of motor symptoms in Parkinson's disease (PD) patients. The pathophysiology of de …
Regulation of neurotoxicity in the striatum and colon of MPTP-induced Parkinson's disease mice by gut microbiome.
Shan J, Qu Y, Wang S, Wei Y, Chang L, Ma L, Hashimoto K. Shan J, et al. Brain Res Bull. 2021 Dec;177:103-110. doi: 10.1016/j.brainresbull.2021.09.009. Epub 2021 Sep 22. Brain Res Bull. 2021. PMID: 34560239
Increasing evidence suggests the role of gut-microbiota-brain axis in the pathogenesis of Parkinson's disease (PD). The objective of this study was to examine whether repeated administration of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) can influence …
Increasing evidence suggests the role of gut-microbiota-brain axis in the pathogenesis of Parkinson's disease (PD). The …
Behavior and electrophysiological effects on striatum-nigra circuit after high frequency stimulation. Relevance to Parkinson and epilepsy.
Tchaikovsky I, Lucena MM, Andrade da Costa BDS, Garcia-Cairasco N, Carelli PV, Cairrao M. Tchaikovsky I, et al. Int J Neurosci. 2023 May;133(5):523-531. doi: 10.1080/00207454.2021.1929216. Epub 2023 Feb 5. Int J Neurosci. 2023. PMID: 34082662
The phenomenon of plasticity in the striatum, and its relation with the striatum-nigra neuronal circuit has clinical and neurophysiological relevance to Parkinson and epilepsy. High frequency stimulation (HFS) can induce neural plasticity. ...Present data are suggestive of …
The phenomenon of plasticity in the striatum, and its relation with the striatum-nigra neuronal circuit has clinical and neurophysiological …
Effects of Aging in the Striatum and Substantia Nigra of a Parkinson's Disease Animal Model.
Ureshino RP, Costa AJ, Erustes AG, Pereira GJDS, Sinigaglia-Coimbra R, Smaili SS. Ureshino RP, et al. Toxicol Pathol. 2018 Apr;46(3):348-358. doi: 10.1177/0192623318767065. Toxicol Pathol. 2018. PMID: 29683090
In this work, we investigated neurodegeneration induced by rotenone, as a pharmacological model of Parkinson's disease, in both young and aged Wistar rats. We assessed animal mobility, tyrosine hydroxylase staining in the substantia nigra pars compacta (SNpc) …
In this work, we investigated neurodegeneration induced by rotenone, as a pharmacological model of Parkinson's disease, …
1,121 results