Magnesium as a preventive treatment for paediatric episodic tension-type headache: results at 1-year follow-up

Neurol Sci. 2007 Jun;28(3):148-50. doi: 10.1007/s10072-007-0808-y. Epub 2007 Jun 30.

Abstract

The objective was to confirm the long-term utility of magnesium salts treatment on a group of young patients suffering from episodic tension-type headache (ETTH). The study was carried out at the Outpatient Headache Center at the National Neurological Institute "C. Besta," Milan, Italy, with 45 children/adolescents with ETTH reporting consecutively for treatment. Magnesium pidolate (2.25 g) was given twice per day for three months. Medication was not administered during the year of follow-up. No other treatment was provided at any time. Patients showed significant symptom reduction. Headache days decreased by 69.9%, whereas analgesics consumption was reduced by 65.4%. Overall disability levels improved by the greatest percent - 75.7%. MIDAS subscores improved as well (question A=58.0%; question B=22.5%). Although uncontrolled, these findings are encouraging and suggest that further, better controlled research investigations are warranted.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Child
  • Female
  • Follow-Up Studies
  • Humans
  • Italy
  • Male
  • Pyrrolidonecarboxylic Acid / therapeutic use*
  • Tension-Type Headache / prevention & control*
  • Treatment Outcome

Substances

  • Pyrrolidonecarboxylic Acid