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A Strong Dose-Response Relation Between Serum Concentrations of Persistent Organic Pollutants and Diabetes: Results From the National Health and Nutrition Examination Survey 1999–2002

Response to Porta

¹ Department of Preventive Medicine and Health Promotion Research Center, School of Medicine, Kyungpook National University, Daegu, Korea
² Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota
³ Department of Nutrition, University of Oslo, Oslo, Norway

Address correspondence to Duk-Hee Lee, MD, PhD, Department of Preventive Medicine, School of Medicine, Kyungpook University, 101 Dongin-dong, Jung-gu, Daegu, Korea 700-422. E-mail: lee_dh@knu.ac.kr

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We thank Dr. Porta (1) for his interest in our study (2). As our study was cross-sectional, a possibility of reverse causality needs to be carefully evaluated. The most critical issue he raised is weight changes, which were not considered in our report. Body weight loss increases both serum and adipose tissue concentrations of persistent organic pollutants (POPs) (3,4), and diabetic patients are advised to attempt weight loss as a nonpharmacologic intervention. Conceivably, . . . [Full Text of this Article]

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				D.-H. Lee, I.-K. Lee, S.-H. Jin, M. Steffes, and D. R. Jacobs Jr. Association Between Serum Concentrations of Persistent Organic Pollutants and Insulin Resistance Among Nondiabetic Adults: Results from the National Health and Nutrition Examination Survey 1999-2002 Diabetes Care, March 1, 2007; 30(3): 622 - 628. [Abstract] [Full Text] [PDF]