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2000 1
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2005 1
2012 1
2014 1
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2020 2
2021 1
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Alcoholic liver disease: new insights in pathogenesis lead to new treatments.
Lieber CS. Lieber CS. J Hepatol. 2000;32(1 Suppl):113-28. doi: 10.1016/s0168-8278(00)80420-1. J Hepatol. 2000. PMID: 10728799 Review.
Much progress has been made in the understanding of the pathogenesis of alcoholic liver disease, resulting in improvement of prevention and therapy, with promising prospects for even more effective treatments. ...PPC is one of the substan …
Much progress has been made in the understanding of the pathogenesis of alcoholic liver disease, resulting in im …
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis.
Parisinos CA, Wilman HR, Thomas EL, Kelly M, Nicholls RC, McGonigle J, Neubauer S, Hingorani AD, Patel RS, Hemingway H, Bell JD, Banerjee R, Yaghootkar H. Parisinos CA, et al. J Hepatol. 2020 Aug;73(2):241-251. doi: 10.1016/j.jhep.2020.03.032. Epub 2020 Apr 2. J Hepatol. 2020. PMID: 32247823 Free PMC article.
BACKGROUND & AIMS: MRI-based corrected T1 (cT1) is a non-invasive method to grade the severity of steatohepatitis and liver fibrosis. We aimed to identify genetic variants influencing liver cT1 and use genetics to understand mechanisms underlying liver fi …
BACKGROUND & AIMS: MRI-based corrected T1 (cT1) is a non-invasive method to grade the severity of steatohepatitis and liver fibro …
Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments.
Kitade H, Chen G, Ni Y, Ota T. Kitade H, et al. Nutrients. 2017 Apr 14;9(4):387. doi: 10.3390/nu9040387. Nutrients. 2017. PMID: 28420094 Free PMC article. Review.
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders worldwide. It is associated with clinical states such as obesity, insulin resistance, and type 2 diabetes, and covers a wide range of liver changes, ranging from …
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders worldwide. It is associated …
New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance.
Karin M. Karin M. Precis Clin Med. 2018 Jun;1(1):21-28. doi: 10.1093/pcmedi/pby005. Epub 2018 Jun 4. Precis Clin Med. 2018. PMID: 30687560 Free PMC article. Review.
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. HCC initiates as a consequence of chronic liver damage and inflammation caused by hepatitis B and C virus infections, excessive alcohol consumption, or non-alcoholic fatt …
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. HCC initiates as a consequence of chronic …
Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment.
Lieber CS. Lieber CS. Am J Addict. 2001;10(s1):s29-s50. doi: 10.1080/10550490150504128. Am J Addict. 2001. PMID: 11268819 Review.
Much progress has been made in the understanding of the pathogenesis of alcoholic liver disease, resulting in improvement of treatment. ...Methionine is normally activated to S-adenosylmethionine (SAMe). However, in liver disease, …
Much progress has been made in the understanding of the pathogenesis of alcoholic liver disease, resulting in im …
Studying non-alcoholic fatty liver disease with zebrafish: a confluence of optics, genetics, and physiology.
Schlegel A. Schlegel A. Cell Mol Life Sci. 2012 Dec;69(23):3953-61. doi: 10.1007/s00018-012-1037-y. Epub 2012 Jun 8. Cell Mol Life Sci. 2012. PMID: 22678663 Free PMC article. Review.
The pathological accumulation of neutral lipids in the liver (hepatic steatosis) is an obesity-related problem whose molecular underpinnings are unknown and whose effective treatment is lacking. ...The highlighted work and future directions may lead to fresh …
The pathological accumulation of neutral lipids in the liver (hepatic steatosis) is an obesity-related problem whose molecular underp …
The nuclear and cytoplasmic roles of miR-320 in non-alcoholic fatty liver disease.
Zhan J, Lv H, Dai B, Yuan S, Fan J, Zhao Y, Yin Z, Wang DW, Chen C, Li H. Zhan J, et al. Aging (Albany NY). 2020 Nov 7;12(21):22019-22045. doi: 10.18632/aging.104040. Epub 2020 Nov 7. Aging (Albany NY). 2020. PMID: 33186123 Free article.
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder worldwide. ...Interestingly, miR-320 affected different target genes in cytosol and nucleus, respectively, which collectively led to liver lipid over …
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder worldwide. ...In …
Mouse models for investigating the underlying mechanisms of nonalcoholic steatohepatitis-derived hepatocellular carcinoma.
Takakura K, Oikawa T, Tomita Y, Mizuno Y, Nakano M, Saeki C, Torisu Y, Saruta M. Takakura K, et al. World J Gastroenterol. 2018 May 14;24(18):1989-1994. doi: 10.3748/wjg.v24.i18.1989. World J Gastroenterol. 2018. PMID: 29760542 Free PMC article. Review.
As the incidence of hepatocellular carcinoma (HCC) caused by infection with the hepatotropic viruses hepatitis B and hepatitis C decreases, greater attention has become focused on HCC caused by nonalcoholic steatohepatitis (NASH), an advanced form of nonalcoholic fatty liver …
As the incidence of hepatocellular carcinoma (HCC) caused by infection with the hepatotropic viruses hepatitis B and hepatitis C decreases, …
Elucidation of SIRT-1/PGC-1alpha-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease.
Jiang Y, Chen D, Gong Q, Xu Q, Pan D, Lu F, Tang Q. Jiang Y, et al. Lipids Health Dis. 2021 Apr 26;20(1):40. doi: 10.1186/s12944-021-01461-5. Lipids Health Dis. 2021. PMID: 33902605 Free PMC article.
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) can lead to chronic liver diseases associated with mitochondrial damages. However, the exact mechanisms involved in the etiology of the disease are not clear. METHODS: To gain …
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) can lead to chronic liver diseases associated with m …
New connections: New targets for fighting hepatic steatosis.
Wong W. Wong W. Sci Signal. 2017 Feb 21;10(467):eaam9988. doi: 10.1126/scisignal.aam9988. Sci Signal. 2017. PMID: 28223420 Review.
Insight into the signaling pathways that regulate de novo lipogenesis may lead to new treatments for hepatic steatosis....
Insight into the signaling pathways that regulate de novo lipogenesis may lead to new treatments for hepatic ste …
16 results