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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1981 1
1984 1
1987 1
1989 3
1990 2
1991 1
1992 3
1993 2
1994 4
1995 2
1996 5
1997 11
1998 9
1999 11
2000 14
2001 16
2002 11
2003 16
2004 12
2005 15
2006 21
2007 16
2008 17
2009 10
2010 20
2011 20
2012 22
2013 23
2014 34
2015 39
2016 33
2017 33
2018 29
2019 33
2020 49
2021 50
2022 34
2023 38
2024 11

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605 results

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Page 1
Sleep and Alzheimer's disease.
Peter-Derex L, Yammine P, Bastuji H, Croisile B. Peter-Derex L, et al. Sleep Med Rev. 2015 Feb;19:29-38. doi: 10.1016/j.smrv.2014.03.007. Epub 2014 Apr 3. Sleep Med Rev. 2015. PMID: 24846773 Review.
Sleep disorders are frequent in Alzheimer's disease (AD), with a significant impact on patients and caregivers and a major risk factor for early institutionalization. ...Management of sleep disorders in AD is pre-eminently behavioral. Association of melatonin …
Sleep disorders are frequent in Alzheimer's disease (AD), with a significant impact on patients and caregivers and a major ris …
Is Melatonin the "Next Vitamin D"?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements.
Minich DM, Henning M, Darley C, Fahoum M, Schuler CB, Frame J. Minich DM, et al. Nutrients. 2022 Sep 22;14(19):3934. doi: 10.3390/nu14193934. Nutrients. 2022. PMID: 36235587 Free PMC article. Review.
Melatonin has become a popular dietary supplement, most known as a chronobiotic, and for establishing healthy sleep. Research over the last decade into cancer, Alzheimer's disease, multiple sclerosis, fertility, PCOS, and many other conditions, combined with …
Melatonin has become a popular dietary supplement, most known as a chronobiotic, and for establishing healthy sleep. Research over th …
Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in AD and Rosacea.
Zhang H, Zhang Y, Li Y, Wang Y, Yan S, Xu S, Deng Z, Yang X, Xie H, Li J. Zhang H, et al. Front Immunol. 2021 Nov 23;12:756550. doi: 10.3389/fimmu.2021.756550. eCollection 2021. Front Immunol. 2021. PMID: 34899707 Free PMC article.
Rosacea is significantly associated with dementia, particularly Alzheimer's disease (AD). However, the common underlying molecular mechanism connecting these two diseases remains limited. ...They were used to predict the therapeutic drugs for rosacea and AD u …
Rosacea is significantly associated with dementia, particularly Alzheimer's disease (AD). However, the common underlyin …
REM sleep behaviour disorder.
Dauvilliers Y, Schenck CH, Postuma RB, Iranzo A, Luppi PH, Plazzi G, Montplaisir J, Boeve B. Dauvilliers Y, et al. Nat Rev Dis Primers. 2018 Aug 30;4(1):19. doi: 10.1038/s41572-018-0016-5. Nat Rev Dis Primers. 2018. PMID: 30166532 Review.
RBD is categorized as either idiopathic RBD or symptomatic (also known as secondary) RBD; the latter is associated with antidepressant use or with neurological diseases, especially alpha-synucleinopathies (such as Parkinson disease, dementia with Lewy bodies and mul …
RBD is categorized as either idiopathic RBD or symptomatic (also known as secondary) RBD; the latter is associated with antidepressant use o …
Pharmacological and non-pharmacological interventions to enhance sleep in mild cognitive impairment and mild Alzheimer's disease: A systematic review.
Blackman J, Swirski M, Clynes J, Harding S, Leng Y, Coulthard E. Blackman J, et al. J Sleep Res. 2021 Aug;30(4):e13229. doi: 10.1111/jsr.13229. Epub 2020 Dec 2. J Sleep Res. 2021. PMID: 33289311 Free PMC article. Review.
Suboptimal sleep causes cognitive decline and probably accelerates Alzheimer's Disease (AD) progression. Several sleep interventions have been tested in established AD dementia cases. ...This systematic review aims to summarize evidence on sleep interventions …
Suboptimal sleep causes cognitive decline and probably accelerates Alzheimer's Disease (AD) progression. Several sleep interve …
Circadian rhythms and disorders of the timing of sleep.
Meyer N, Harvey AG, Lockley SW, Dijk DJ. Meyer N, et al. Lancet. 2022 Sep 24;400(10357):1061-1078. doi: 10.1016/S0140-6736(22)00877-7. Epub 2022 Sep 14. Lancet. 2022. PMID: 36115370 Review.
New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation.
Zisapel N. Zisapel N. Br J Pharmacol. 2018 Aug;175(16):3190-3199. doi: 10.1111/bph.14116. Epub 2018 Jan 15. Br J Pharmacol. 2018. PMID: 29318587 Free PMC article. Review.
Clinically meaningful effects of melatonin treatment have been demonstrated in placebo-controlled trials in humans, particularly in disorders associated with diminished or misaligned melatonin rhythms, for example, circadian rhythm-related sleep disorders, jet lag a …
Clinically meaningful effects of melatonin treatment have been demonstrated in placebo-controlled trials in humans, particularly in d …
Importance of Bmal1 in Alzheimer's disease and associated aging-related diseases: Mechanisms and interventions.
Fan R, Peng X, Xie L, Dong K, Ma D, Xu W, Shi X, Zhang S, Chen J, Yu X, Yang Y. Fan R, et al. Aging Cell. 2022 Oct;21(10):e13704. doi: 10.1111/acel.13704. Epub 2022 Sep 3. Aging Cell. 2022. PMID: 36056774 Free PMC article. Review.
With the aging world population, the prevalence of aging-related disorders is on the rise. Diseases such as Alzheimer's, type 2 diabetes mellitus (T2DM), Parkinson's, atherosclerosis, hypertension, and osteoarthritis are age-related, and most of these diseases are comorbid …
With the aging world population, the prevalence of aging-related disorders is on the rise. Diseases such as Alzheimer's, type 2 diabe …
The role of melatonin in the treatment of type 2 diabetes mellitus and Alzheimer's disease.
Shen S, Liao Q, Wong YK, Chen X, Yang C, Xu C, Sun J, Wang J. Shen S, et al. Int J Biol Sci. 2022 Jan 1;18(3):983-994. doi: 10.7150/ijbs.66871. eCollection 2022. Int J Biol Sci. 2022. PMID: 35173531 Free PMC article. Review.
Studies have shown that such inflammation and impaired insulin signaling contribute to the development of Alzheimer's disease (AD). Therefore, new therapeutic strategies are needed for the treatment of T2DM and T2DM-linked AD. ...Besides rhythm-related effects, m …
Studies have shown that such inflammation and impaired insulin signaling contribute to the development of Alzheimer's disease …
Melatonin: A review of its potential functions and effects on neurological diseases.
Gunata M, Parlakpinar H, Acet HA. Gunata M, et al. Rev Neurol (Paris). 2020 Mar;176(3):148-165. doi: 10.1016/j.neurol.2019.07.025. Epub 2019 Nov 11. Rev Neurol (Paris). 2020. PMID: 31718830 Review.
Neurological disease deaths have risen 36% worldwide in 25 years. Melatonin is a neuroregulator hormone that has free radical scavenger, strong antioxidant, anti-inflammatory, and immunosuppressive actions. ...Both preventive and therapeutic effects of melatonin …
Neurological disease deaths have risen 36% worldwide in 25 years. Melatonin is a neuroregulator hormone that has free radical …
605 results