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The hepatitis B vaccine

young child being held by adult while receiving vaccination in arm
Photo credit: Heather Hazzan, SELF Magazine

What are the benefits of the hepatitis B vaccine?

The hepatitis B vaccine (HepB) protects your child against the hepatitis B virus, which can lead to liver damage and even death.

Hepatitis B is generally considered an adult disease because it's often transmitted through unsafe sex and shared needles. But many people who get it – including children – don't engage in these high-risk behaviors. They're either infected at birth or they contract the disease during childhood from close contact with another person who is infected.

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Each year, an estimated 25,000 babies are born to moms with Hepatitis B, and around 1,000 women transmit the disease to their babies. That's why pregnant women are routinely tested for Hepatitis B so doctors can take steps if necessary to protect their newborns, and vaccinations against hepatitis B start at birth.

Many people with Hepatitis B never feel sick and don't know they have the disease, but those who become infected as children are more likely to have long-term health problems, such as cirrhosis and liver cancer. An estimated 862,000 people in the United States have chronic hepatitis B. In 2017, more than 1,700 Americans died from illnesses related to hepatitis B.

The hepatitis B vaccine was introduced in 1981 and became part of the recommended immunization schedule in the United States in 1991. Since then, the incidence of acute hepatitis B has dropped by more than 95 percent in children and adolescents, and by about 82 percent overall.

The number of new infections annually has declined from an average of 260,000 in the 1980s to an estimated 12,200 in 2017. The biggest decline was among children and adolescents.

Recommended number of doses

Three shots

Recommended ages

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  • At birth
  • Between 1 and 2 months
  • Between 6 and 18 months

Women in the United States are screened for hepatitis B during pregnancy. If you test positive, your baby should get an injection of hepatitis B immune globulin (HBIG), as well as the hepatitis B vaccine, within 12 hours of birth to provide short-term protection.

To track your child's immunizations, use BabyCenter's Immunization Scheduler.

Who should not get the hepatitis B vaccine?

A child who had a life-threatening allergic reaction to a previous dose of hepatitis B vaccine should not be vaccinated with it again.

If your child didn't get hepatitis B shots as a baby, and she's had a life-threatening allergic reaction to baker's yeast (the kind used in bread), she shouldn't receive the hepatitis B vaccine because it's made with that type of yeast.

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Are there any precautions I should take?

In general, the hepatitis B vaccine isn't as effective in infants with low birth weight, such as preemies if they get it before they're 1 month old. If your child is born underweight, talk to the doctor to find out when your baby can get the vaccine.

All children who are moderately to severely ill should wait until they recover before getting the hepatitis B vaccine.

What are the possible side effects?

Some children feel soreness at the injection site, and a few develop a low-grade fever. Severe allergic reactions are rare but possible with any vaccine.

See what our expert says about how to tell whether your child is having an adverse reaction.

If your child has an adverse reaction to this or any other vaccine, talk to your child's doctor and report it to the Vaccine Adverse Event Reporting SystemOpens a new window.

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Find out more about other vaccines and immunizations recommended for babies.

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BabyCenter's editorial team is committed to providing the most helpful and trustworthy pregnancy and parenting information in the world. When creating and updating content, we rely on credible sources: respected health organizations, professional groups of doctors and other experts, and published studies in peer-reviewed journals. We believe you should always know the source of the information you're seeing. Learn more about our editorial and medical review policies.

CDC. 2019. Vaccine information statement: Hepatitis B. U.S. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/hcp/vis/vis-statements/hep-b.htmlOpens a new window [Accessed July 2020]

CDC. 2020. Viral hepatitis: Hepatitis B information. U.S. Centers for Disease Control and Prevention. http://www.cdc.gov/hepatitis/hbv/Opens a new window [Accessed July 2020]

HHS. 2019. Hepatitis B Basic Information. U.S. Department of Health and Human Services. https://www.hhs.gov/hepatitis/learn-about-viral-hepatitis/hepatitis-b-basics/index.htmlOpens a new window [Accessed July 2020]

Eva Dasher
Eva Dasher writes, researches, and edits content on a wide variety of subjects, including parenting, medicine, travel, natural history, science, business, and the arts. Her favorite pastimes include experimenting with new foods, libations, and restaurants, as well as traveling the world with her two college-age children, husband, extended family, and friends.
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