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[Observations of characteristics of the mechanisms of biological oxidation of cell wall-deficient bacteria]
[Article in Chinese]
Wang H, Cheng Z.
Department of Microbiology, Guiyang Medical College, Guiyang 550004.
The L-forms were induced from Staphylococcus aureus, Escherichia coli and Bacillus cereus by beta-lactam antibiotics and then observations on the properties of oxygen requirement, sugar fermentation and sensitive to cyanide of the L-forms were done. The results were shown that the L-forms derived from the obligate aerobe or the facultative anaerobe did not ferment sugars and were highly oxygen-dependent and more sensitive to cyanide than their parent bacteria. The metabolic activities which were same as the parent bacteria of the L-forms would return after the L-forms reverted to the typical bacteria forms. It was possible that the changes of biological oxidation mechanism were due to the deficiency of the cell wall which led to loss of the periplasmic space or the membrane-wall interlayer so that the enzymes for fermentation existed in the space could not be hold.
Publication Types:
PMID: 12549407 [PubMed - indexed for MEDLINE]