LOCUS NC_002953 2799802 bp DNA circular BCT 23-JUL-2008 DEFINITION Staphylococcus aureus subsp. aureus MSSA476, complete genome. ACCESSION NC_002953 VERSION NC_002953.3 GI:49484912 PROJECT GenomeProject:266 KEYWORDS complete genome. SOURCE Staphylococcus aureus subsp. aureus MSSA476 ORGANISM Staphylococcus aureus subsp. aureus MSSA476 Bacteria; Firmicutes; Bacillales; Staphylococcus. REFERENCE 1 (bases 1 to 2799802) AUTHORS Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Dowd,L., Feltwell,T., Hance,Z., Harris,B., Hauser,H., Holroyd,S., Jagels,K., James,K.D., Lennard,N., Line,A., Mayes,R., Moule,S., Mungall,K., Ormond,D., Quail,M.A., Rabbinowitsch,E., Rutherford,K., Sanders,M., Sharp,S., Simmonds,M., Stevens,K., Whitehead,S., Barrell,B.G., Spratt,B.G. and Parkhill,J. TITLE Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (26), 9786-9791 (2004) PUBMED 15213324 REFERENCE 2 (bases 1 to 2799802) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (11-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (bases 1 to 2799802) AUTHORS Holden,M.T.G. TITLE Direct Submission JOURNAL Submitted (23-JUN-2004) Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: mh3@sanger.ac.uk COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BX571857. On Jun 30, 2004 this sequence version replaced gi:27532930. COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..2799802 /organism="Staphylococcus aureus subsp. aureus MSSA476" /mol_type="genomic DNA" /strain="MSSA476" /db_xref="taxon:282459" gene 517..1878 /gene="dnaA" /locus_tag="SAS0001" /db_xref="GeneID:2862485" CDS 517..1878 /gene="dnaA" /locus_tag="SAS0001" /note="binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself." /codon_start=1 /transl_table=11 /product="chromosomal replication initiation protein" /protein_id="YP_042134.1" /db_xref="GI:49484913" /db_xref="GeneID:2862485" gene 2156..3289 /locus_tag="SAS0002" /db_xref="GeneID:2863534" CDS 2156..3289 /locus_tag="SAS0002" /EC_number="2.7.7.7" /note="binds the polymerase to DNA and acts as a sliding clamp" /codon_start=1 /transl_table=11 /product="DNA polymerase III subunit beta" /protein_id="YP_042135.1" /db_xref="GI:49484914" /db_xref="GeneID:2863534" gene 3670..3915 /locus_tag="SAS0003" /db_xref="GeneID:2863844" CDS 3670..3915 /locus_tag="SAS0003" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0003" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042136.1" /db_xref="GI:49484915" /db_xref="GeneID:2863844" gene 3912..5024 /gene="recF" /locus_tag="SAS0004" /db_xref="GeneID:2863845" CDS 3912..5024 /gene="recF" /locus_tag="SAS0004" /note="Required for DNA replication; binds preferentially to single-stranded, linear DNA" /codon_start=1 /transl_table=11 /product="recombination protein F" /protein_id="YP_042137.1" /db_xref="GI:49484916" /db_xref="GeneID:2863845" gene 5037..6968 /locus_tag="SAS0005" /db_xref="GeneID:2863525" CDS 5037..6968 /locus_tag="SAS0005" /EC_number="5.99.1.3" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0005" /codon_start=1 /transl_table=11 /product="DNA gyrase subunit B" /protein_id="YP_042138.1" /db_xref="GI:49484917" /db_xref="GeneID:2863525" gene 7005..9668 /locus_tag="SAS0006" /db_xref="GeneID:2863526" CDS 7005..9668 /locus_tag="SAS0006" /EC_number="5.99.1.3" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0006" /codon_start=1 /transl_table=11 /product="DNA gyrase subunit A" /protein_id="YP_042139.1" /db_xref="GI:49484918" /db_xref="GeneID:2863526" gene complement(9755..10585) /locus_tag="SAS0007" /db_xref="GeneID:2863330" CDS complement(9755..10585) /locus_tag="SAS0007" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0007" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042140.1" /db_xref="GI:49484919" /db_xref="GeneID:2863330" gene 10893..12407 /gene="hutH" /locus_tag="SAS0008" /db_xref="GeneID:2862922" CDS 10893..12407 /gene="hutH" /locus_tag="SAS0008" /EC_number="4.3.1.3" /note="catalyzes the degradation of histidine to urocanate and ammmonia" /codon_start=1 /transl_table=11 /product="histidine ammonia-lyase" /protein_id="YP_042141.1" /db_xref="GI:49484920" /db_xref="GeneID:2862922" gene 12493..12725 /locus_tag="SASs001" /db_xref="GeneID:2863607" misc_RNA 12493..12725 /locus_tag="SASs001" /note="T-box leader as predicted by Rfam (RF00230), score 85.48" /db_xref="GeneID:2863607" gene 12786..14072 /locus_tag="SAS0009" /db_xref="GeneID:2862923" CDS 12786..14072 /locus_tag="SAS0009" /EC_number="6.1.1.11" /note="catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA" /codon_start=1 /transl_table=11 /product="seryl-tRNA synthetase" /protein_id="YP_042142.1" /db_xref="GI:49484921" /db_xref="GeneID:2862923" gene 14724..15419 /locus_tag="SAS0010" /db_xref="GeneID:2863128" CDS 14724..15419 /locus_tag="SAS0010" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0010" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042143.1" /db_xref="GI:49484922" /db_xref="GeneID:2863128" gene 15416..15745 /locus_tag="SAS0011" /db_xref="GeneID:2862973" CDS 15416..15745 /locus_tag="SAS0011" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0011" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042144.1" /db_xref="GI:49484923" /db_xref="GeneID:2862973" gene 15949..16047 /locus_tag="SASs002" /db_xref="GeneID:2864305" misc_RNA 15949..16047 /locus_tag="SASs002" /note="SAM riboswitch (S box leader) as predicted by Rfam (RF00162), score 80.12" /db_xref="GeneID:2864305" gene 16108..17076 /locus_tag="SAS0012" /db_xref="GeneID:2862974" CDS 16108..17076 /locus_tag="SAS0012" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0012" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="YP_042145.1" /db_xref="GI:49484924" /db_xref="GeneID:2862974" gene 17321..18307 /locus_tag="SAS0013" /db_xref="GeneID:2862977" CDS 17321..18307 /locus_tag="SAS0013" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0013" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042146.1" /db_xref="GI:49484925" /db_xref="GeneID:2862977" gene 18322..20289 /locus_tag="SAS0014" /db_xref="GeneID:2862982" CDS 18322..20289 /locus_tag="SAS0014" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0014" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042147.1" /db_xref="GI:49484926" /db_xref="GeneID:2862982" gene 20286..20732 /gene="rplI" /locus_tag="SAS0015" /db_xref="GeneID:2862983" CDS 20286..20732 /gene="rplI" /locus_tag="SAS0015" /note="in Escherichia coli this protein is wrapped around the base of the L1 stalk" /codon_start=1 /transl_table=11 /product="50S ribosomal protein L9" /protein_id="YP_042148.1" /db_xref="GI:49484927" /db_xref="GeneID:2862983" gene 20764..22164 /locus_tag="SAS0016" /db_xref="GeneID:2862860" CDS 20764..22164 /locus_tag="SAS0016" /EC_number="3.6.1.-" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0016" /codon_start=1 /transl_table=11 /product="replicative DNA helicase" /protein_id="YP_042149.1" /db_xref="GI:49484928" /db_xref="GeneID:2862860" gene 22443..23726 /locus_tag="SAS0017" /db_xref="GeneID:2862094" CDS 22443..23726 /locus_tag="SAS0017" /EC_number="6.3.4.4" /note="catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis" /codon_start=1 /transl_table=11 /product="adenylosuccinate synthetase" /protein_id="YP_042150.1" /db_xref="GI:49484929" /db_xref="GeneID:2862094" gene 24156..24230 /locus_tag="SASt001" /db_xref="GeneID:2863949" tRNA 24156..24230 /locus_tag="SASt001" /product="tRNA-Glu" /note="tRNA Glu anticodon TTC, Cove score 76.88" /db_xref="GeneID:2863949" gene 24238..24310 /locus_tag="SASt002" /db_xref="GeneID:2864023" tRNA 24238..24310 /locus_tag="SASt002" /product="tRNA-Asp" /note="tRNA Asp anticodon GTC, Cove score 75.02" /db_xref="GeneID:2864023" gene 24924..25631 /locus_tag="SAS0018" /db_xref="GeneID:2862095" CDS 24924..25631 /locus_tag="SAS0018" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0018" /codon_start=1 /transl_table=11 /product="response regulator protein" /protein_id="YP_042151.1" /db_xref="GI:49484930" /db_xref="GeneID:2862095" gene 25644..27470 /locus_tag="SAS0019" /db_xref="GeneID:2861788" CDS 25644..27470 /locus_tag="SAS0019" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0019" /codon_start=1 /transl_table=11 /product="sensor kinase protein" /protein_id="YP_042152.1" /db_xref="GI:49484931" /db_xref="GeneID:2861788" gene 27463..28797 /locus_tag="SAS0020" /db_xref="GeneID:2863016" CDS 27463..28797 /locus_tag="SAS0020" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0020" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042153.1" /db_xref="GI:49484932" /db_xref="GeneID:2863016" gene 28798..29586 /locus_tag="SAS0021" /db_xref="GeneID:2863017" CDS 28798..29586 /locus_tag="SAS0021" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0021" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042154.1" /db_xref="GI:49484933" /db_xref="GeneID:2863017" gene 29975..30775 /locus_tag="SAS0022" /db_xref="GeneID:2863002" CDS 29975..30775 /locus_tag="SAS0022" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0022" /codon_start=1 /transl_table=11 /product="metallo-beta-lactamase superfamily protein" /protein_id="YP_042155.1" /db_xref="GI:49484934" /db_xref="GeneID:2863002" gene 30961..33321 /locus_tag="SAS0023" /db_xref="GeneID:2861765" CDS 30961..33321 /locus_tag="SAS0023" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0023" /codon_start=1 /transl_table=11 /product="putative 5'-nucleotidase" /protein_id="YP_042156.1" /db_xref="GI:49484935" /db_xref="GeneID:2861765" gene 33689..34168 /locus_tag="SAS0024" /db_xref="GeneID:2861766" CDS 33689..34168 /locus_tag="SAS0024" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0024" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042157.1" /db_xref="GI:49484936" /db_xref="GeneID:2861766" gene complement(34546..37584) /locus_tag="SAS0025" /db_xref="GeneID:2861763" CDS complement(34546..37584) /locus_tag="SAS0025" /note="N-terminus is similar to the N_terminal region of Escherichia coli type I restriction enzyme EcoR124II R protein HsdR or Hsr SWALL:T1R1_ECOLI (SWALL:P10486) (1033 aa) fasta scores: E(): 2.1e-05, 22.57% id in 762 aa. Full length CDS is similar to Caulobacter crescentus hypothetical protein CC0623 SWALL:Q9AAH5 (EMBL:AE005738) (964 aa) fasta scores: E(): 2.5e-103, 37.74% id in 959 aa" /codon_start=1 /transl_table=11 /product="putative type I restriction enzyme protein" /protein_id="YP_042158.1" /db_xref="GI:49484937" /db_xref="REBASE:SauMSSORF27P" /db_xref="GeneID:2861763" gene complement(37588..38898) /locus_tag="SAS0026" /db_xref="GeneID:2864389" CDS complement(37588..38898) /locus_tag="SAS0026" /note="Similar to Escherichia coli type I restriction enzyme EcoBI specificity protein HsdS or Hss SWALL:T1SB_ECOLI (SWALL:P06990) (474 aa) fasta scores: E(): 3.7e-10, 21.44% id in 443 aa, and to Caulobacter crescentus type I restriction-modification system, S subunit CC0621 SWALL:Q9AAH7 (EMBL:AE005738) (450 aa) fasta scores: E(): 9.9e-18, 23.18% id in 440 aa" /codon_start=1 /transl_table=11 /product="putative type I restriction enzyme specificity protein" /protein_id="YP_042159.1" /db_xref="GI:49484938" /db_xref="GeneID:2864389" gene complement(38891..40678) /locus_tag="SAS0027" /db_xref="GeneID:2864390" CDS complement(38891..40678) /locus_tag="SAS0027" /note="Similar to Escherichia coli type I restriction enzyme EcoR124II M protein HsdM or Hsm SWALL:T1M1_ECOLI (SWALL:P10484) (520 aa) fasta scores: E(): 8.6e-16, 23.81% id in 504 aa, and to Caulobacter crescentus type I restriction-modification system, M subunit, putative CC0620 SWALL:Q9AAH8 (EMBL:AE005738) (611 aa) fasta scores: E(): 2.1e-72, 42.97% id in 605 aa" /codon_start=1 /transl_table=11 /product="putative type I restriction enzyme methylase protein" /protein_id="YP_042160.1" /db_xref="GI:49484939" /db_xref="GeneID:2864390" gene complement(40866..41087) /locus_tag="SAS0028" /db_xref="GeneID:2864039" CDS complement(40866..41087) /locus_tag="SAS0028" /note="Similar to Staphylococcus aureus hypothetical 9.2 kDa protein SWALL:Q93IA3 (EMBL:AB037671) (80 aa) fasta scores: E(): 1.1e-24, 89.04% id in 73 aa, and to Staphylococcus aureus hypothetical 8.0 kDa protein SWALL:Q93ID7 (EMBL:AB037671) (68 aa) fasta scores: E(): 0.0037, 33.33% id in 54 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042161.1" /db_xref="GI:49484940" /db_xref="GeneID:2864039" gene complement(41101..41604) /locus_tag="SAS0029" /db_xref="GeneID:2863985" CDS complement(41101..41604) /locus_tag="SAS0029" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0056 Similar to Staphylococcus aureus hypothetical protein SA0054 SWALL:Q99XD7 (EMBL:AP003358) (172 aa) fasta scores: E(): 2.6e-59, 94.61% id in 167 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042162.1" /db_xref="GI:49484941" /db_xref="GeneID:2863985" gene complement(41620..41931) /locus_tag="SAS0030" /db_xref="GeneID:2863986" CDS complement(41620..41931) /locus_tag="SAS0030" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0057 Similar to Staphylococcus hominis hypothetical protein Orf11 SWALL:Q8VUW8 (EMBL:AB063171) (103 aa) fasta scores: E(): 1.7e-36, 93.2% id in 103 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042163.1" /db_xref="GI:49484942" /db_xref="GeneID:2863986" gene complement(42024..42365) /locus_tag="SAS0031" /db_xref="GeneID:2862750" CDS complement(42024..42365) /locus_tag="SAS0031" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0058 Similar to Staphylococcus aureus hypothetical 13.8 kDa protein SWALL:Q9LBZ1 (EMBL:AB033763) (116 aa) fasta scores: E(): 3.7e-44, 96.42% id in 112 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042164.1" /db_xref="GI:49484943" /db_xref="GeneID:2862750" gene complement(42831..44456) /gene="ccrB" /locus_tag="SAS0032" /db_xref="GeneID:2864289" CDS complement(42831..44456) /gene="ccrB" /locus_tag="SAS0032" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0059 Similar to Staphylococcus hominis site-specific recombinase CcrB1 SWALL:BAB83487 (EMBL:AB063171) (542 aa) fasta scores: E(): 2.8e-179, 95.01% id in 542 aa, and to Staphylococcus aureus cassette chromosome recombinase B CcrB or CcrB3 SWALL:Q9R3U2 (EMBL:AB014437) (542 aa) fasta scores: E(): 4.3e-163, 85.79% id in 542 aa" /codon_start=1 /transl_table=11 /product="site-specific recombinase" /protein_id="YP_042165.1" /db_xref="GI:49484944" /db_xref="GeneID:2864289" gene complement(44478..45827) /gene="ccrA1" /locus_tag="SAS0033" /db_xref="GeneID:2864288" CDS complement(44478..45827) /gene="ccrA1" /locus_tag="SAS0033" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0060 Similar to Staphylococcus hominis site-specific recombinase CcrA1 SWALL:Q8VUX1 (EMBL:AB063171) (449 aa) fasta scores: E(): 1e-161, 94.87% id in 449 aa, and to Staphylococcus aureus cassette chromosome recombinase A1 CcrA1 SWALL:Q9S0L6 (EMBL:AB033763) (449 aa) fasta scores: E(): 3.6e-161, 94.65% id in 449 aa" /codon_start=1 /transl_table=11 /product="site-specific recombinase" /protein_id="YP_042166.1" /db_xref="GI:49484945" /db_xref="GeneID:2864288" gene complement(46015..47784) /locus_tag="SAS0034" /db_xref="GeneID:2861797" CDS complement(46015..47784) /locus_tag="SAS0034" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0061 Similar to Staphylococcus hominis DNA, cassette chromosome SCC, strain:ATCC27844 hypothetical protein SWALL:Q8VUX3 (EMBL:AB063171) (589 aa) fasta scores: E(): 2.5e-202, 89.47% id in 589 aa, and to Staphylococcus aureus hypothetical protein SWALL:Q9S0L7 (EMBL:AB033763) (589 aa) fasta scores: E(): 1e-201, 88.79% id in 589 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042167.1" /db_xref="GI:49484946" /db_xref="GeneID:2861797" gene complement(47784..48080) /locus_tag="SAS0035" /db_xref="GeneID:2861798" CDS complement(47784..48080) /locus_tag="SAS0035" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0062 Similar to Staphylococcus aureus hypothetical 11.1 kDa protein SWALL:Q9LBZ5 (EMBL:AB033763) (98 aa) fasta scores: E(): 1e-34, 88.77% id in 98 aa, and to Staphylococcus hominis DNA, cassette chromosome scc, strain:ATCC27844 hypothetical protein SWALL:Q8VUX4 (EMBL:AB063171) (98 aa) fasta scores: E(): 7.5e-33, 84.69% id in 98 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042168.1" /db_xref="GI:49484947" /db_xref="GeneID:2861798" gene complement(48253..49740) /locus_tag="SAS0036" /db_xref="GeneID:2863284" CDS complement(48253..49740) /locus_tag="SAS0036" /note="Poor database matches. N-terminus is similar to the N-terminal region of Ureaplasma parvum hypothetical membrane lipoprotein UU125 SWALL:Q9PR19 (EMBL:AE002113) (394 aa) fasta scores: E(): 0.0071, 23.33% id in 330 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042169.1" /db_xref="GI:49484948" /db_xref="GeneID:2863284" gene 49912..50616 /locus_tag="SAS0037" /db_xref="GeneID:2863371" CDS 49912..50616 /locus_tag="SAS0037" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042170.1" /db_xref="GI:49484949" /db_xref="GeneID:2863371" gene 50640..51482 /locus_tag="SAS0038" /db_xref="GeneID:2863372" CDS 50640..51482 /locus_tag="SAS0038" /note="Poor database matches C-terminal region is similar to Brucella melitensis hypothetical protein BMEI1674 SWALL:Q8YF53 (EMBL:AE009602) (250 aa) fasta scores: E(): 1e-10, 32.61% id in 233 aa. CDS contains a coiled-coil region, residues 62 to 85" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042171.1" /db_xref="GI:49484950" /db_xref="GeneID:2863372" gene 51926..52234 /locus_tag="SAS0040" /db_xref="GeneID:2863375" CDS 51926..52234 /locus_tag="SAS0040" /note="No significant database matches. Doubtful CDS" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042172.1" /db_xref="GI:49484951" /db_xref="GeneID:2863375" gene 52820..53458 /locus_tag="SAS0043" /db_xref="GeneID:2863381" CDS 52820..53458 /locus_tag="SAS0043" /note="Similar to Staphylococcus aureus fusidic acid resistance protein Far1 SWALL:Q8GNY5 (EMBL:AF468686) (213 aa) fasta scores: E(): 7.8e-28, 43.68% id in 206 aa" /codon_start=1 /transl_table=11 /product="putative fusidic acid resistance protein" /protein_id="YP_042173.1" /db_xref="GI:49484952" /db_xref="GeneID:2863381" gene 54144..54773 /locus_tag="SAS0044" /db_xref="GeneID:2863382" CDS 54144..54773 /locus_tag="SAS0044" /note="Similar to Xylella fastidiosa hypothetical protein XF0543 SWALL:Q9PFW4 (EMBL:AE003901) (222 aa) fasta scores: E(): 0.0072, 26.94% id in 219 aa. N-terminal region is similar to Streptococcus pneumoniae hypothetical protein SP1047 SWALL:Q97QZ5 (EMBL:AE007407) (105 aa) fasta scores: E(): 9.9e-07, 38.09% id in 105 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042174.1" /db_xref="GI:49484953" /db_xref="GeneID:2863382" gene complement(55452..55880) /locus_tag="SAS0046" /db_xref="GeneID:2863358" CDS complement(55452..55880) /locus_tag="SAS0046" /note="Similar to Escherichia coli phnB protein PhnB SWALL:PHNB_ECOLI (SWALL:P16681) (147 aa) fasta scores: E(): 0.046, 22.55% id in 133 aa, and to Clostridium acetobutylicum uncharacterized conserved protein, phnb family CAC3689 SWALL:Q97D00 (EMBL:AE007864) (137 aa) fasta scores: E(): 3.3e-06, 31.49% id in 127 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042175.1" /db_xref="GI:49484954" /db_xref="GeneID:2863358" gene 55960..56889 /locus_tag="SAS0047" /db_xref="GeneID:2862655" CDS 55960..56889 /locus_tag="SAS0047" /note="Similar to Bacillus halodurans hypothetical protein BH1889 SWALL:Q9KBN6 (EMBL:AP001513) (325 aa) fasta scores: E(): 5.2e-16, 25.71% id in 315 aa, and to Listeria monocytogenes hypothetical protein LMO0364 SWALL:Q8YA03 (EMBL:AL591975) (314 aa) fasta scores: E(): 1.7e-15, 24.44% id in 315 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042176.1" /db_xref="GI:49484955" /db_xref="GeneID:2862655" gene 57181..58476 /locus_tag="SAS0048" /db_xref="GeneID:2862656" CDS 57181..58476 /locus_tag="SAS0048" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0025 Similar to Staphylococcus aureus region mecA element hypothetical protein Orf1260 SWALL:Q9KJC5 (EMBL:AF181950) (419 aa) fasta scores: E(): 2.2e-138, 93.51% id in 416 aa. Weakly similar to Listeria monocytogenes hypothetical protein LMO0304 SWALL:Q8YA57 (EMBL:AL591974) (421 aa) fasta scores: E(): 2.1e-18, 27.65% id in 434 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042177.1" /db_xref="GI:49484956" /db_xref="GeneID:2862656" gene complement(58948..59577) /locus_tag="SAS0049" /pseudo /db_xref="GeneID:2863455" gene complement(59745..59855) /locus_tag="SAS0050" /pseudo /db_xref="GeneID:2862634" gene 60231..60956 /gene="seh" /locus_tag="SAS0051" /db_xref="GeneID:2862465" CDS 60231..60956 /gene="seh" /locus_tag="SAS0051" /note="Identical to Staphylococcus aureus enterotoxin H Seh SWALL:Q53585 (EMBL:U11702) (241 aa) fasta scores: E(): 1.2e-84, 100% id in 241 aa. Similar to Staphylococcus aureus enterotoxin type E precursor EntE SWALL:ETXE_STAAU (SWALL:P12993) (257 aa) fasta scores: E(): 2.1e-21, 37.05% id in 251 aa" /codon_start=1 /transl_table=11 /product="enterotoxin H" /protein_id="YP_042178.1" /db_xref="GI:49484957" /db_xref="GeneID:2862465" gene 61523..61711 /locus_tag="SAS0052" /pseudo /db_xref="GeneID:2862635" gene 61852..62325 /locus_tag="SAS0053" /db_xref="GeneID:2863440" CDS 61852..62325 /locus_tag="SAS0053" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0098" /codon_start=1 /transl_table=11 /product="acetyltransferase (GNAT) family protein" /protein_id="YP_042179.1" /db_xref="GI:49484958" /db_xref="GeneID:2863440" gene complement(62876..63631) /locus_tag="SAS0054" /db_xref="GeneID:2862672" CDS complement(62876..63631) /locus_tag="SAS0054" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0048" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042180.1" /db_xref="GI:49484959" /db_xref="GeneID:2862672" gene complement(63631..63897) /locus_tag="SAS0055" /db_xref="GeneID:2862673" CDS complement(63631..63897) /locus_tag="SAS0055" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0047" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042181.1" /db_xref="GI:49484960" /db_xref="GeneID:2862673" gene 64028..65095 /locus_tag="SAS0056" /db_xref="GeneID:2863478" CDS 64028..65095 /locus_tag="SAS0056" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0046" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042182.1" /db_xref="GI:49484961" /db_xref="GeneID:2863478" gene 65126..66460 /locus_tag="SAS0057" /db_xref="GeneID:2863462" CDS 65126..66460 /locus_tag="SAS0057" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0044" /codon_start=1 /transl_table=11 /product="metallo-beta-lactamase superfamily protein" /protein_id="YP_042183.1" /db_xref="GI:49484962" /db_xref="GeneID:2863462" gene 66479..67672 /locus_tag="SAS0058" /db_xref="GeneID:2863463" CDS 66479..67672 /locus_tag="SAS0058" /note="Similar to the C-terminal region of Schizosaccharomyces pombe sulfide:quinone oxidoreductase, mitochondrial precursor HMT2 or CAD1 or SPBC2G5.06c SWALL:HMT2_SCHPO (SWALL:O94284) (459 aa) fasta scores: E(): 9.1e-52, 39.36% id in 409 aa, and to the full length Bacillus cereus sulfide-quinone reductase bc3512 SWALL:Q81AP8 (EMBL:AE017009) (399 aa) fasta scores: E(): 3.3e-87, 54.7% id in 393 aa" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="YP_042184.1" /db_xref="GI:49484963" /db_xref="GeneID:2863463" gene complement(68339..69325) /locus_tag="SAS0059" /db_xref="GeneID:2863645" CDS complement(68339..69325) /locus_tag="SAS0059" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0099" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042185.1" /db_xref="GI:49484964" /db_xref="GeneID:2863645" gene 69634..69837 /locus_tag="SAS0060" /db_xref="GeneID:2863051" CDS 69634..69837 /locus_tag="SAS0060" /note="Similar to the C-terminal region of Bacillus anthracis hypothetical protein ba2438 SWALL:Q81QI7 (EMBL:AE017031) (81 aa) fasta scores: E(): 2.2, 33.87% id in 62 aa. Weakly similar to Escherichia coli microcin M imunity protein McmI SWALL:Q83TS3 (EMBL:AJ515251) (73 aa) fasta scores: E(): 7.7, 27.77% id in 54 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042186.1" /db_xref="GI:49484965" /db_xref="GeneID:2863051" gene 69886..70182 /locus_tag="SAS0061" /db_xref="GeneID:2863052" CDS 69886..70182 /locus_tag="SAS0061" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0101" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042187.1" /db_xref="GI:49484966" /db_xref="GeneID:2863052" gene complement(70254..71474) /locus_tag="SAS0062" /db_xref="GeneID:2862602" CDS complement(70254..71474) /locus_tag="SAS0062" /note="Similar to Lactobacillus plantarum transport protein lp_0492 SWALL:Q88Z68 (EMBL:AL935253) (403 aa) fasta scores: E(): 1.4e-51, 38.02% id in 405 aa, and to Bacillus anthracis permease, putative ba2277 SWALL:Q81QY7 (EMBL:AE017031) (409 aa) fasta scores: E(): 1.2e-17, 20.84% id in 403 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042188.1" /db_xref="GI:49484967" /db_xref="GeneID:2862602" gene complement(71467..72024) /locus_tag="SAS0063" /db_xref="GeneID:2863027" CDS complement(71467..72024) /locus_tag="SAS0063" /note="Similar to Bacillus subtilis hypothetical protein YwqN SWALL:P96726 (EMBL:Z92952) (181 aa) fasta scores: E(): 1.8e-24, 39.22% id in 181 aa, and to Bacillus cereus trp repressor binding protein bc5177 SWALL:Q815H5 (EMBL:AE017014) (181 aa) fasta scores: E(): 1.4e-23, 40.11% id in 177 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042189.1" /db_xref="GI:49484968" /db_xref="GeneID:2863027" gene 72131..72991 /locus_tag="SAS0064" /db_xref="GeneID:2863028" CDS 72131..72991 /locus_tag="SAS0064" /note="Similar to Bacillus anthracis transcriptional regulator, LysR family ba3543 SWALL:Q81YK0 (EMBL:AE017035) (297 aa) fasta scores: E(): 8.1e-19, 29.31% id in 290 aa. C-terminus is similar to the C-terminal region of Bacillus subtilis transcriptional regulatory protein GltR or bsu26670 SWALL:GLTR_BACSU (SWALL:P94501) (296 aa) fasta scores: E(): 3.2e-13, 27.98% id in 243 aa" /codon_start=1 /transl_table=11 /product="LysR family regulatory protein" /protein_id="YP_042190.1" /db_xref="GI:49484969" /db_xref="GeneID:2863028" gene complement(73346..73879) /locus_tag="SAS0065" /db_xref="GeneID:2863424" CDS complement(73346..73879) /locus_tag="SAS0065" /note="Similar to Bacillus anthracis hypothetical protein BA1938 SWALL:Q81RU9 (EMBL:AE017030) (182 aa) fasta scores: E(): 1.8e-27, 45.05% id in 182 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042191.1" /db_xref="GI:49484970" /db_xref="GeneID:2863424" gene 73979..74713 /locus_tag="SAS0066" /db_xref="GeneID:2864070" CDS 73979..74713 /locus_tag="SAS0066" /note="Similar to Bacillus anthracis transcriptional regulator, LysR family ba1937 SWALL:Q81RV0 (EMBL:AE017030) (262 aa) fasta scores: E(): 2.5e-11, 28.9% id in 256 aa. C-terminus is similar to the C-terminal region of Bacillus subtilis transcriptional regulatory protein GltR or bsu26670 SWALL:GLTR_BACSU (SWALL:P94501) (296 aa) fasta scores: E(): 5.7e-06, 26.05% id in 238 aa" /codon_start=1 /transl_table=11 /product="LysR family regulatory protein" /protein_id="YP_042192.1" /db_xref="GI:49484971" /db_xref="GeneID:2864070" gene 75138..75749 /locus_tag="SAS0067" /db_xref="GeneID:2864071" CDS 75138..75749 /locus_tag="SAS0067" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0102" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042193.1" /db_xref="GI:49484972" /db_xref="GeneID:2864071" gene 76016..79168 /locus_tag="SAS0068" /db_xref="GeneID:2863061" CDS 76016..79168 /locus_tag="SAS0068" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0103" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042194.1" /db_xref="GI:49484973" /db_xref="GeneID:2863061" gene 79225..79707 /locus_tag="SAS0069" /db_xref="GeneID:2863617" CDS 79225..79707 /locus_tag="SAS0069" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0104" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042195.1" /db_xref="GI:49484974" /db_xref="GeneID:2863617" gene 79912..80897 /gene="plc" /locus_tag="SAS0070" /pseudo /db_xref="GeneID:2863295" gene 81118..81888 /locus_tag="SAS0072" /db_xref="GeneID:2863618" CDS 81118..81888 /locus_tag="SAS0072" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0106" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="YP_042196.1" /db_xref="GI:49484975" /db_xref="GeneID:2863618" gene 81940..82710 /locus_tag="SAS0073" /db_xref="GeneID:2863677" CDS 81940..82710 /locus_tag="SAS0073" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="YP_042197.1" /db_xref="GI:49484976" /db_xref="GeneID:2863677" gene 82989..83753 /locus_tag="SAS0074" /db_xref="GeneID:2864298" CDS 82989..83753 /locus_tag="SAS0074" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="YP_042198.1" /db_xref="GI:49484977" /db_xref="GeneID:2864298" gene 83756..85132 /locus_tag="SAS0075" /db_xref="GeneID:2864299" CDS 83756..85132 /locus_tag="SAS0075" /note="Weakly similar to Listeria monocytogenes hypothetical protein lmo2804 SWALL:Q8Y3N1 (EMBL:AL591984) (427 aa) fasta scores: E(): 3.9e-10, 25.56% id in 442 aa, and Listeria innocua hypothetical protein lin2936 SWALL:Q926V4 (EMBL:AL596174) (427 aa) fasta scores: E(): 1.4e-08, 24.44% id in 454 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042199.1" /db_xref="GI:49484978" /db_xref="GeneID:2864299" gene 85132..85458 /locus_tag="SAS0076" /db_xref="GeneID:2862233" CDS 85132..85458 /locus_tag="SAS0076" /note="Poor database matches. Weakly similar to Streptococcus agalactiae hypothetical protein gbs1827 SWALL:Q8E3D2 (EMBL:AL766853) (130 aa) fasta scores: E(): 5.7, 25.77% id in 97 aa" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042200.1" /db_xref="GI:49484979" /db_xref="GeneID:2862233" gene 85462..85773 /locus_tag="SAS0077" /db_xref="GeneID:2864086" CDS 85462..85773 /locus_tag="SAS0077" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042201.1" /db_xref="GI:49484980" /db_xref="GeneID:2864086" gene 86025..88262 /locus_tag="SAS0078" /db_xref="GeneID:2864087" CDS 86025..88262 /locus_tag="SAS0078" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0107" /codon_start=1 /transl_table=11 /product="putative regulatory protein" /protein_id="YP_042202.1" /db_xref="GI:49484981" /db_xref="GeneID:2864087" gene 88413..89591 /locus_tag="SAS0079" /db_xref="GeneID:2864226" CDS 88413..89591 /locus_tag="SAS0079" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0108" /codon_start=1 /transl_table=11 /product="putative peptidase" /protein_id="YP_042203.1" /db_xref="GI:49484982" /db_xref="GeneID:2864226" gene 89593..90981 /locus_tag="SAS0080" /db_xref="GeneID:2864296" CDS 89593..90981 /locus_tag="SAS0080" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0109" /codon_start=1 /transl_table=11 /product="putative transporter protein" /protein_id="YP_042204.1" /db_xref="GI:49484983" /db_xref="GeneID:2864296" gene complement(91468..93135) /locus_tag="SAS0081" /db_xref="GeneID:2864297" CDS complement(91468..93135) /locus_tag="SAS0081" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0110" /codon_start=1 /transl_table=11 /product="putative Na+/Pi-cotransporter protein" /protein_id="YP_042205.1" /db_xref="GI:49484984" /db_xref="GeneID:2864297" gene complement(93453..95228) /locus_tag="SAS0082" /db_xref="GeneID:2862282" CDS complement(93453..95228) /locus_tag="SAS0082" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0111" /codon_start=1 /transl_table=11 /product="putative myosin-crossreactive antigen" /protein_id="YP_042206.1" /db_xref="GI:49484985" /db_xref="GeneID:2862282" gene 95579..96052 /locus_tag="SAS0083" /db_xref="GeneID:2864112" CDS 95579..96052 /locus_tag="SAS0083" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0112" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_042207.1" /db_xref="GI:49484986" /db_xref="GeneID:2864112" gene 96314..97906 /locus_tag="SAS0084" /db_xref="GeneID:2864113" CDS 96314..97906 /locus_tag="SAS0084" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0113" /codon_start=1 /transl_table=11 /product="L-lactate permease 1" /protein_id="YP_042208.1" /db_xref="GI:49484987" /db_xref="GeneID:2864113" gene complement(98235..99713) /locus_tag="SAS0085" /db_xref="GeneID:2864145" CDS complement(98235..99713) /locus_tag="SAS0085" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0114" /codon_start=1 /transl_table=11 /product="immunoglobulin G binding protein A precursor" /protein_id="YP_042209.1" /db_xref="GI:49484988" /db_xref="GeneID:2864145" gene complement(100134..100886) /locus_tag="SAS0086" /db_xref="GeneID:2862258" CDS complement(100134..100886) /locus_tag="SAS0086" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0115" /codon_start=1 /transl_table=11 /product="putative regulatory protein" /protein_id="YP_042210.1" /db_xref="GI:49484989" /db_xref="GeneID:2862258" gene complement(101255..102253) /locus_tag="SAS0087" /db_xref="GeneID:2862259" CDS complement(101255..102253) /locus_tag="SAS0087" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0116" /codon_start=1 /transl_table=11 /product="putative siderophore transport system permease" /protein_id="YP_042211.1" /db_xref="GI:49484990" /db_xref="GeneID:2862259" gene complement(102250..103245) /locus_tag="SAS0088" /db_xref="GeneID:2864148" CDS complement(102250..103245) /locus_tag="SAS0088" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0117" /codon_start=1 /transl_table=11 /product="putative siderophore transport system permease" /protein_id="YP_042212.1" /db_xref="GI:49484991" /db_xref="GeneID:2864148" gene complement(103261..104253) /locus_tag="SAS0089" /db_xref="GeneID:2862594" CDS complement(103261..104253) /locus_tag="SAS0089" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0118" /codon_start=1 /transl_table=11 /product="lipoprotein" /protein_id="YP_042213.1" /db_xref="GI:49484992" /db_xref="GeneID:2862594" gene 104484..105464 /locus_tag="SAS0090" /db_xref="GeneID:2862595" CDS 104484..105464 /locus_tag="SAS0090" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0119" /codon_start=1 /transl_table=11 /product="pyridoxal-phosphate dependent enzyme" /protein_id="YP_042214.1" /db_xref="GI:49484993" /db_xref="GeneID:2862595" gene 105461..106471 /locus_tag="SAS0091" /db_xref="GeneID:2861951" CDS 105461..106471 /locus_tag="SAS0091" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0120" /codon_start=1 /transl_table=11 /product="putative ornithine cyclodeaminase" /protein_id="YP_042215.1" /db_xref="GI:49484994" /db_xref="GeneID:2861951" gene 106492..108246 /locus_tag="SAS0092" /db_xref="GeneID:2861960" CDS 106492..108246 /locus_tag="SAS0092" /note="Ortholog of S. aureus MRSA252 (BX571856) SAR0121" /codon_start=1 /transl_table=11 /product="putative siderophore biosynthesis protein" /protein_id="